lumefantrine will lessen the level or result of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.nevirapine will decrease the level or result of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. The efficacy of hormonal contraceptives could be reduceā€¦ Read More